MsClear Depth Filter

Applied in clarification and downstream filtraation processes

Depth filtration is oftenused for pre-filtration, such as fermentation broth clarification,removal of cell debris and DNA, pre-treatment of blood products and other biological products, etc. The MsClear Depth Filter, specially developed for high-demand clarification application in the biotechnology and pharmaceutical industries, can significantly reduce the difficulty of downstream purification.

Product Features

• Made of diatomaceous earth and cellulose, with ultra-high dirt holding capacity
• Higher impurity removal capacity through mechanical interception and electrostatic adsorption
• Combines multiple clarification steps into one device, optimizing theclarification process
• Offers full range of products for process scale-up and scale-down

Filter Applications

• Clarification filtration of fermentation broth and cell culture fluid
• Filtration of blood products
• Removal of impurities in chemical drugs, decarbonization filtration
• Removal ofparticles and gels from process intermediates

Clarification Filtration

The purpose of clarification is to effectively separate cells, celldebris, and other colloidal substances from the harvested liquid, providing impurity-free feed for downstream purification. Clarification of cell harvest fluid is the first step in downstream purification in biopharmaceutical processes, usually using a combination of centrifugation, tangential flow filtration, flocculation, and depth filtration. Depth fitration technology isincreasingly favored in the industry for its ability to improve product quality and simplify operations. The harvested clarification filtration typically uses two-stage depth depth filtration: the first stage uses a larger poresize filter to remove cells or cell debris; the second stage uses a tighter pore size medium to remove colloidal impurities.

Ms Depth Filtration

To meet different process needs, Membrane Solutions has developed the MsClear P series and S series depthfilters. The filter media inside the filters are the same as those in traditional depth filtration system, with various precision and model choices. Additionally, MsClear occupies a small area, saving cleanroom space. Compared to traditional depth filtration system, MsClear is flexible in installation and easy to operate, suitable for process development.

Product Pictures

Product Parameter Table

From process development to large-scale production, Membrane Solutions provides suitable solutions for you.

Accuracy

Ordering Information

Holder and Accessories

Various specifications of depth holder to suit different disk packspecifications and meet different process needs.

Product Features

Compared to similar products on the market, the holder provided by Membrane Solutions can precisely adjust the pressure.

Product Parameters

Specification	10m²Holder	3m²Holder
Picture
Length/Width/Height	775*575*1740mm	580*530*1000mm
Weight	Approx.178kg	Approx.73kg
Capacity	1m²*10	1m²*3
Surface Finish	ra3.2	ra3.2
Adjustable Torque	5-35N ·M	5-35N ·M

Ordering Information