UltraMemTM Nuggets TFF Cassettes

Request a Quote

Product Description

Membrane Solutions can provide tangential filtration solutions, the UltraMem Nuggets TFF cassettes, for our customers, to fulfill the needs in bio-pharmaceutical applications. UltraMem Nuggets cassettes are composed of UltraMem high performance UF membranes. It is a high performance tangential flow filter product with safety, convenience and cost efficiency for bio-pharm and bio-tech process.Typical applications of UltraMem Nugget cassettes include but no limited to the concentration and separation of monoclonal antibiotics, recombinant protein drugs, virus-vectors, vaccines, plasmid, mRNA LNP, particulate dispersions, cell culture clarications, buffer exchange, etc.

Specifictions

  • Fast and reliable linear amplication from the lab to production scale

  • Robust and reliable design enables UltraMem Nuggets to withstand high pressure and temperature (max 5bar@40℃)

  • Easy to operate, fast installation and cleaning, ensure reliable yield; <10% ux decline after 200 hrs caustic wash; Max 210g/L concentration can be achieved
  • Broad chemical compatibility
  • Multiple MWCOs and/or pore size to choose, combined with multiple process area, and membrane materials, meet your demands

Quality Assurance

  • All materials and components of UltraMem Nuggets cassette, as well as UltraMem membranes are composed of biosafe materials, which meet requirements of USP <87> and USP <88>
  • UltraMem Nuggets cassettes are manufactured in controlled environment and under the quality systems that meet GMP requirements
  • 100% integrity tests and visual inspections are conducted prior to product release, ensuring each cassette is integral, intact and meet high quality standards

Parameters

Membrane Type Modifed PES Regenerated Cellulose
Filtration Type UF MF UF
MWCO 5/8/10/30/50/70/100/300/500 kD 0.1/0.2/0.45 μm 1/2/3/10/30/100/300 kD
Flow Rate Fast Medium
Static Protein Adsorption Low Very Low
pH Range 1-14 2-13
Recommendations Fast process of protein solutions;       
harsh process and cleaning conditions		 Viscous and high conc.%liquid,where high recovery is demanded
Materials of Construction
Housing Silicone (Soft) Resin(Rigid)
Membrane Modifed PES with nonwoven support Regenerated Cellulose with nonwoven support
Channel/Fleece Polypropylene Polypropylene
Preservation Liquid 20%glycerol+0.05 M NaOH 20%glycerol+0.05 M NaOH
Operating
Housing Silicone (Soft) Resin(Rigid)
Maximum Inlet Pressure 5.5bar@25℃;4 bar@40℃ 5.5 bar@25℃;5 bar@40℃
Operating pH Range 1-14 for PES membrane,2-13 for RC membrane

Dimensions

Filtration Area Silicone (Soft)         Resin(Rigid) Processing Volumes
100 cm² L/W/H:205×56×2 L/W/H:205×56×4 100-1000 ml
0.1 m² L/W/H:205×56×16 L/W/H:205×56×16 0.2-10L
0.5 m² L/W/H:205×173×17 L/W/H:205×178×16 >2L
2.5 m² L/W/H:205×173×88 L/W/H:205×178×72 >10L

Ordering Information

FMC

E

100

D

PI

SS

Catalog

Membrane Type

MWCO

Channel

Scale

Housing

FMC=UltraMemTMNugget
TFF Cassette
for
BioPharm
Process

E=PES
C=Regenerated
Cellulose

001=1 kDa    070=70 kDa
002=2 kDa    100=100 kDa
003=3 kDa    300=300 kDa
005=5 kDa    500=500 kDa
008=8 kDa    011=0.1 μm
010=10 kDa  022=0.2 μm
030=30 kDa  045=0.45 μm
050=50 kDa  

D=Channel D
V=Channel V

LA=Lab, 100 cm2
PI=Pilot, 0.1 m2
PR=Process, 0.5 m2
PP=Process Plus, 2.5 m2

SS=silicone(soft)
RR=Resin(rigid)
 

Related Products

Hollow Fiber Filters

UltraMem50 Crossflow Cassette

UltraMemTM Nuggets TFF Cassettes