UltraMem™ Nuggets TFF Cassettes

Membrane Solutions can provide tangential filtration solutions, the UltraMem Nuggets TFF cassettes, for our customers, to fulfill the needs in bio-pharmaceutical applications. UltraMem Nuggets cassettes are composed of UltraMem high performance UF membranes. It is a high performance tangential flow filter product with safety, convenience and cost efficiency for bio-pharm and bio-tech process.Typical applications of UltraMem Nugget cassettes include but no limited to the concentration and separation of monoclonal antibiotics, recombinant protein drugs, virus-vectors, vaccines, plasmid, mRNA LNP, particulate dispersions, cell culture clarications, buffer exchange, etc.
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Specs Number Description Price

Related Documents

NuggetMem TFF Cassette Validation Guide NuggetMem TFF Cassettes Datasheet NuggetMem TFF Cassettes User Manual

 

Features

  • Fast and reliable linear amplication from the lab to production scale
  • Robust and reliable design enables UltraMem Nuggets to withstand high pressure and temperature (max 5bar@40℃)
  • Easy to operate, fast installation and cleaning, ensure reliable yield; <10% ux decline after 200 hrs caustic wash; Max 210g/L concentration can be achieved
  • Broad chemical compatibility
  • Multiple MWCOs and/or pore size to choose, combined with multiple process area, and membrane materials, meet your demands

Applications

  • Concentration of biomolecules (recombinant proteins, monoclonal antibodies, viruses, etc.)
  • Dialysis, desalination, and buffer replacement
  • Separation and purification
  • Remove endotoxins
  • Except for macromolecules, etc

Technical Parameters

 

Composition
Material		 Membrane PES/PVDF
Support Polyolefin
Fleece PP
Packaging Materials Silicone
Gasket Silicone
Operation
Condition		 Maximum Operating Pressure 5.5bar@50℃
Maximum TMP 4.0bar@50℃
Operating Temperature 4-50℃
Operating pH 1-14
Recommended Process Flow Rate 4.0-6.0L/m2/min
Recommended Cleaning Flow Rate 8.0-10.0L/m2/min
Integrity
Testing		 Test Method Diffusion Flow (Air)
Test Conditions 1.0bar@25℃
Test Standards ≤100mL/min/m
Information
Regulatory		 Biosafety All materials and components of NuggetMemTM cassettes
meet requirements of USP <87> and USP <88>.
Insoluble Particles Complies with USP<778>standards
Endotoxins ＜0.25EU/mL
Quality System Follow the quality management systems of ISO9001 and ISO13485.
Production conditions Complies with GMP regulatory requirements,100% product integrity testing and visual inspection.

Notes：

Traceability: Each cassette is assigned a unique serial number for complete traceability.

Packaging includes one quality guarantee certificate, two silicone gaskets, and the user manual, MSDS and validation guide are available from Membrane Solutions upon request.

Packaging and protective liquid:** The aluminum foil bag is vacuum-sealed, and the cassette packaging contains a 25% glycerol aqueous solution with 0.2N sodium hydroxide.**

Area (㎡） L/W/H(mm) Application
0.01  210.0×55.5×1.7 R&D, Lab
0.02  210.0×55.5×3.4 R&D, Lab
0.10  210.0×55.5×15.0 R&D, Lab, Pilot
0.50  213.0×178.0×16.0 Pilot, Process
1.00  213.0×318.0×16.0 Pilot, Process
2.50  213.0×178.0×75.0 Pilot, Process
5.00  213.0×318.0×75.0 Pilot, Process

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