MS Hydrophilic PES Membrane

MS polyethersulfone (PES) membranes are produced using a unique process, and compared to other membrane varieties, PES membranes have very good water wettability, so PES membranes have extremely high water flux. PES membranes exhibit very low protein adsorption capacity and are widely used in sterilization and filtration of liquids and filtration and clarification in food, medicine and other fields.
Full Description

Online Ordering

*Some specialized product specifications are not displayed. For further details, please click here leave us a message.
Specs Number Description Price

Related Documents
Hydrophilic PES Membrane Datasheet

  

Features

The surface of the hydrophilic PES membrane is uniform, the pore size distribution is narrow, and the separation accuracy is high. The membrane cross-section is a network sponge structure, which has higher anti-fouling ability than the ordinary membrane cross-section finger pore structure, and at the same time, this sponge structure has high mechanical strength, breaking strength > 400cN, and longer service life.

  • High strength
  • High flow rate
  • Low extractable
  • Low protein binding
  • Retention rate: 0.22>7LRV (Brevundimonas diminuta)；0.45>7LRV (Serratia marcescens)
  • The pore size distribution is narrow
  • Sterilization: autoclaving, EO or gamma
  • Biosafety meets USP 87 < in vitro cytotoxic > and USP 88 Class VI < implantable medical raw material > standards

Applications

  • General filtration
  • Sterile filtration
  • IV therapy
  • Pharmaceutical filtration
  • Bacterial isolation

Technical Parameters

Membrane Material

PES

Wetting Performance

hydrophilic

Support

None

Structure

Asymmetry

Thickness

100-130um

Width

260mm/500mm

Length

100-200m

chemical Performance

Excellent

Operation pH

2-12

Sterilization

Autoclaving, ethylene oxide, Gamma

Pore Size

0.05/0.1/0.22/0.45/0.65/0.8/1.0/1.2/3.0/5.0μm

Membrane Testing Reports Available

Bubble Point and Flow Test Report
Pore Size Analysis Report
SEM
FTIR

Contact Angle Test
Bacterial Retention Test Report
HPLC Test Report

Tensile Strength Test Report

FAQ

Basic Characteristics and Selection

1.What material is the PES membrane made of, and what are its core advantages?

PES stands for polyethersulfone. It features strong hydrophilicity, high flow rate, low protein binding, and steam sterilization resistance, making it suitable for aqueous solutions and biological sample filtration.

2.What are the common pore sizes of PES membranes and their respective applications?

Common pore sizes: 0.05 / 0.1 / 0.22 / 0.45 / 0.8 / 1.0 / 5.0μm.

  • 0.22μm: Sterilizing filtration (pharmacopoeia grade, retains Brevundimonas diminuta)
  • 0.45μm: Clarification, particle removal, microbiological testing
  • 0.1μm: Mycoplasma/virus retention, ultrapure water polishing

3.What temperature and sterilization methods can the PES membrane withstand?

It can withstand steam sterilization at 121°C / 0.1MPa; continuous operation ≤ 80°C. It is not resistant to strong oxidizing agents (e.g., concentrated nitric acid, high concentration sodium hypochlorite).

4.What is the chemical compatibility of PES membranes, and which solvents cannot be used?

Compatible with most aqueous solutions, buffers, alcohols, weak acids/alkalis. Not compatible with strong polar aprotic solvents (DMSO, DMF, DMAc), ketones (acetone), halogenated hydrocarbons, concentrated strong acids/alkalis.

Applications and Operation

1.What samples are PES suitable for filtering, and for what is it not suitable?

Suitable for: culture media, serum, protein solutions, vaccines, buffers, injections, purified water. Not suitable for: strong organic solvents, gas/steam filtration, high-viscosity oily samples.

2.What to do if filtration is slow or the filter clogs easily?

① Centrifuge or pre-filter the sample (PP cotton/glass fiber). ② Choose a larger pore size (e.g., 0.45μm for clarification). ③ Control pressure ≤ 0.2MPa and apply pressure slowly. ④ Perform chemical cleaning (0.1M NaOH / 0.5% sodium hypochlorite, circulate at 40°C for 30 min).

3.Causes and solutions for turbid filtrate or microbial contamination?

Causes: membrane damage, poor seal, operational contamination, integrity failure. Solutions: ① Perform integrity test before installation (bubble point/diffusion flow). ② Inspect O-rings and tighten filter. ③ Use sterile technique in a clean bench. ④ Replace with a new membrane.

4.How to deal with the low recovery rate (adsorption) of the target substance?

PES has low adsorption, but further steps:① Pre-wet and saturate with buffer or sample. ② Shorten filtration time. ③ If needed, switch to specialized low-adsorption PES.

Maintenance and Troubleshooting

1.How to clean and regenerate PES membranes?

① Physical: backflush with purified water/filtrate at ≤ 0.2MPa. ② Chemical: for protein fouling, use 0.1% NaOH + 0.5% NaClO, circulate at 40°C for 30 min. ③ After cleaning, flush thoroughly with purified water and pass an integrity test before reuse.

2.When must the PES membrane be replaced?

① Differential pressure ≥ 0.2MPa. ② Flow rate decline > 30%. ③ Membrane damaged, deformed, or yellowed. ④ Sterilization/retention performance fails to meet requirements.