Centrifugal Filter

Centrifugal Filter Description

The centrifugal filter devices provide rapid and efficient concentration and purification of up to 15ml of biological samples. The unique vertical design and maximum filtration area provide fast sample processing and high sample recovery rate (typically greater than 90% of dilute starting solution), while maintaining a gentle concentration environment to pre-serve protein activity and conformation. Solute polarization and subsequent fouling of the membrane are minimized by the vertical design,and a physical dead stop in the filter device prevents spinning to dryness and potential sample loss. The wide selection of ultra filtration molecular weight cut-off (MWCO) devices incorporate PES membrane, which is very low in protein and nucleic acid binding.

MS RevoSeizer™ centrifugal filter catalog

Feature

• High recovery and flow rate;

• Low bio-molecule binding rate, high chemical compatibility;

• Anti-drainage locking design prevents damage to samples caused by over-centrifuging;

• Variety of pore size specifications to meet different MWCO requirements.

Application

Ultra-filtration centrifugal filter:

• Concentrate and desalt proteins, nucleic acids

• Buffer exchange or desalting of chromatographi components

• Harvest bio-molecules from culture media

• Virus concentration or isolation

• Coarse separation of bio-molecule mixtures

• Removal of debris and particles from cell lysates

Micro-filtration centrifugal filter:

• Isolate DNA from agarose gel

• Separation of proteins, oligonucleotides and RNA from polyacrylamide gels

• Sample clarification before HPLC analysis

• Media removal of cells

• Filter biological samples

• Collect and clean processed particles or beads

• Fill chromatography media for analytical procedures or process development

Technical Specifications

Ordering Information